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Potential roles of neutrophils in maintaining the health and productivity of dairy cows during various physiological and physiopathological conditions: a review

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Title Potential roles of neutrophils in maintaining the health and productivity of dairy cows during various physiological and physiopathological conditions: a review
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Subject Neutrophil activity . Expression . Tissue remodelling . Homeostasis . Inflammatory disease
 
Description Not Available
Neutrophils represent the first line of innate immunity and are the most prominent line of cellular defence against invading
microorganisms. On stimulation, they can quickly move through the walls of veins and into the tissues of the body to immediately
attack or monitor the foreign antigens. Neutrophils are highly versatile and sophisticated cells which are endowed with highly
sensitive receptor-based perception systems. They were traditionally classified as short-lived phagocytes actively involved during
infection and inflammation, but recently, it has been seen that neutrophils are capable of detecting the presence of sperms during
insemination as well as an implanting embryo in the female reproductive tract. These specialised phagocytes play a major role in
tissue remodelling and wound healing, and maintain homeostasis during parturition, expulsion of placenta, folliculogenesis,
corpus luteum formation and luteolysis. Here, we review the role played by neutrophils in maintaining homeostasis during
normal and inflammatory conditions of dairy cattle. We have summarised the alteration in the expression of some cell adhesion
molecules and cytokines on bovine neutrophils during different physiological and physiopathological conditions. Some emerging
issues in the field of neutrophil biology and the possible strategies to strengthen their activity during the period of immunosuppression
have also been discussed.
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Date 2021-08-09T05:32:21Z
2021-08-09T05:32:21Z
2020-01-14
 
Type Research Paper
 
Identifier Not Available
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http://krishi.icar.gov.in/jspui/handle/123456789/53711
 
Language English
 
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Publisher Not Available