Record Details


Field	Value

Title	Immunological attributes of blood and milk neutrophils isolated from crossbred cows during different physiological conditions Not Available

Creator	Not Available

Subject	phagocytic; chemotactic activity; cortisol; IL-8; CXCR1; selectin; integrin

Description	Not Available The goal of this work was to understand how polymorphonuclear leukocytes (PMN), the first line of cellular defence, integrate and prioritize multiple chemotactic signals to navigate during periods of demand like subclinical mastitis (SCM), clinical mastitis (CM), pregnancy (P), and calving (C). For this, blood and milk samples were collected from five groups of crossbred cows (healthy, with SCM, CM, pregnant, and newly calved). Maximum viability was seen in the PMN of healthy cows, whereas minimum viability was observed in CM cows. Phagocytic activity (PA) of blood and milk PMN decreased significantly (P < 0.05) at C and in CM cows. Chemotactic activity of blood PMN was minimum in C followed by CM, SCM, and P cows. PA was found to be negatively correlated with the plasma cortisol levels and inverse relationship was observed between the plasma interleukin-8 (IL-8) levels and the chemotactic activity of neutrophils. There was a significantly (P Not Available

Date	2021-08-26T08:13:03Z 2021-08-26T08:13:03Z 2016-02-23

Type	Research Paper

Identifier	Not Available Not Available http://krishi.icar.gov.in/jspui/handle/123456789/60623

Language	English

Relation	Not Available;

Publisher	Not Available

ICAR Research Data Repository for Knowledge Management