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Anti-cancerous Activities of Anthocyanins of Banana cv. Nendran (Musa sp.) Flower Bracts against Human Colon and Cervical Cancer Cell Lines.

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Title Anti-cancerous Activities of Anthocyanins of Banana cv. Nendran (Musa sp.) Flower Bracts against Human Colon and Cervical Cancer Cell Lines.
 
Creator Suman, R., K. Kalaimathi, R. Suman, S. Palanichamy, R. Sowmiya, M. Mayil Vaganan, I. Ravi and Uma, S
 
Subject Anthocyanins, Ant-cancerous, Banana, cv. Nendran, Flower bract,
 
Description Anti-cancerous properties of anthocyanins extracted from banana (cv. Nendran) bract has been discussed.
A comparative study on the anticancer effects of anthocyanins derived from banana cv. Nendran flower bracts against human colon (HT-29) and cervical cancer (HeLa) cells were investigated. In vitro assays by MTT, AO/EtBr and MMP revealed that anthocyanins extract inhibited the growth of both HT-29 and HeLa cells. The percentage of cell viability decreased linearly with the increment of anthocyanins. The IC50 values for anthocyanins were 41.18 µg/ml for colon cancer cells and 46.50 µg/ml for cervical cancer cells by MTT assay. The MMP assay indicated IC50 values of 71.18 and 106.5 µg/ml respectively for HT-29 cells and HeLa cells. The study demonstrates that anthocyanins of banana flower bracts are potential anti-cancerous compounds.
ICAR
 
Date 2022-11-14T11:26:08Z
2022-11-14T11:26:08Z
2018-12-10
 
Type Article
 
Identifier Suman, R., K. Kalaimathi, R. Suman, S. Palanichamy, R. Sowmiya, M. Mayil Vaganan, I. Ravi and Uma, S. (2018). Anti-cancerous Activities of Anthocyanins of Banana cv. Nendran (Musa sp.) Flower Bracts against Human Colon and Cervical Cancer Cell Lines. Int. J. Curr. Microbiol. App. Sci. 7 (12): 2786-2793.
2319-7692
http://krishi.icar.gov.in/jspui/handle/123456789/75114
 
Language English
 
Relation Not Available;
 
Publisher Excellent Publishers