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Evaluation of genotoxicity of profenofos freshwater fish Channa punctatus (Bloch) using the micronucleus assay

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Title Evaluation of genotoxicity of profenofos freshwater fish Channa punctatus (Bloch) using the micronucleus assay
Not Available
 
Creator A. K. Pandey
N. S. Nagpure
S. P. Trivedi
 
Subject genotoxicity
profenofos
channa punctatus
dna damage
micronucleus assay
 
Description Not Available
The present study investigates the genotoxicity of profenofos (PFF), an
organophosphate pesticide in erythrocyte cells of freshwater fish, Channa punctata (Bloch)
using micronucleus assay. The 96 h LC 50 value of PFF (50% EC) was estimated for the fish
species in a semistatic system and then 50% of LC 50 was determined as 1.15 ppb. The fish
specimens were exposed to 1.15 ppb sublethal concentration of the pesticide and
samplings were done on 24, 48, 72 and 96 h post exposure for assessment of DNAby micronucleus assay. The study confirms that PFF is toxic for aquatic organism and the micronucleus assay is a useful tool in determining the potential genotoxicity and mutagenicity of xenobiotic compounds and can be considered as sensitive parameter for toxicity monitoring program.
Not Available
 
Date 2017-06-29T09:00:20Z
2017-06-29T09:00:20Z
2014-09-24
 
Type Research Paper
 
Identifier Pandey, A.K., Nagpure, N.S. and Trivedi, S.P., 2014. Evaluation of genotoxicity of profenofos to freshwater fish Channa punctatus (Bloch) using the micronucleus assay. African Journal of Biotechnology, 13(39).
1684-5315
http://krishi.icar.gov.in/jspui/handle/123456789/4503
 
Language English
 
Relation Not Available;
 
Publisher ACADEMICJOURNALS