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Metallothionein mRNA expression in freshwater teleost, Channa punctata (Bloch) under the influence of heavy metal, cadmium – a dose kinetic study

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Title Metallothionein mRNA expression in freshwater teleost, Channa punctata (Bloch) under the influence of heavy metal, cadmium – a dose kinetic study
Not Available
 
Creator Mohit Tiwari
Naresh Sahebrao Nagpure
Devendra Nath Saksena
Wazir Singh Lakra
 
Subject Cadmium
Channa punctata
Dose response
Metallothionein
Tissue specific
 
Description Not Available
Increased Metallothionein (MT) synthesis is associated with increased capacity for binding metals such as copper, zincand cadmium, as well as protection against metal toxicity. A study was carried out using quantitative real-time reversetranscriptase polymerase chain reaction (q-RT-PCR) in freshwater teleost, Channa punctata (Bloch), after exposure to sub-lethal concentrations of cadmium. Post 14 days exposure, the heightened MT mRNA expression was seen only in kidney, whereas in contaminated liver and gills, the MT gene expression collapsed significantly below the basal level.The difference in the effect of various concentrations of cadmium on MT mRNA transcript level in the tissues under study was found significant. The study indicates that the expression of MT mRNA in C. punctata occurs in tissue specific and dose dependent manner.
University Grants Commission, New Delhi, India
 
Date 2017-07-24T06:22:25Z
2017-07-24T06:22:25Z
2011
 
Type Research Paper
 
Identifier Tiwari, M., Nagpure, N.S., Saksena, D.N. and Lakra, W.S., 2011. Metallothionein mRNA expression in freshwater teleost, Channa punctata (Bloch) under the influence of heavy metal, cadmium—a dose kinetic study. Int Aquat Res, 3, pp.21-29.
2008-4935
http://krishi.icar.gov.in/jspui/handle/123456789/4941
 
Language English
 
Relation Not Available;
 
Publisher Islamic Azad University, Tonekabon