ICAR Research Data Repository for Knowledge Management
Protective effect of L-glutamin on lysosomal integrity in isoproterenol-induced myocardial infarction in rats
KRISHI: Publication and Data Inventory Repository
View Archive Info| Field | Value | |
| Title |
Protective effect of L-glutamin on lysosomal integrity in isoproterenol-induced myocardial infarction in rats
Not Available |
|
| Creator |
R. Anandan
S.H. Senthil Kumar E.S. Sumi S. Mathew Ganesan. B |
|
| Subject |
glutamine, isoproterenol, lysosomal hydrolases, myocardial infarction
|
|
| Description |
Not Available
Lysosomal acid hydrolases play an imperative part in the initiation of inflammation processes associated with myocardial infarction. In the present investigation, we have studied the protective effect of L-glutamine on isoproterenol-induced myocardial damage in male albino rats with respect to alterations in lysosomal function. The myocardial infarction in experimental animals was induced by intraperitoneal (i.p.) injection of isoproterenol (11 mg/100 g body weight/day) for 2 days. The total and free activities of lysosomal acid hydrolases (β-glucuronidase, β-galactosidase, β-glucosidase and acid phosphatase) were determined in plasma and heart tissue of control and treated rats. Significant elevation in the total activities of lysosomal hydrolases was observed in plasma and heart tissue of isoproterenol administered rats. A parallel (p Not Available |
|
| Date |
2017-01-05T08:24:16Z
2017-01-05T08:24:16Z 2015-06-01 |
|
| Type |
Research Paper
|
|
| Identifier |
Acta Biologica Szegediensis 2015; 59(2):205-209.
0236-5383 http://krishi.icar.gov.in/jspui/handle/123456789/1056 |
|
| Language |
English
|
|
| Relation |
Not Available;
|
|
| Publisher |
Hungarian Academy of Sciences
|
|