Record Details

Synthesis and Screening of Anilides Having Olefinic and Alkyl Moiety in the Side Chain as Chemical Hybridizing Agents for Wheat ( Triticum aestivum L.)

KRISHI: Publication and Data Inventory Repository

View Archive Info
 
 
Field Value
 
Title Synthesis and Screening of Anilides Having Olefinic and Alkyl
Moiety in the Side Chain as Chemical Hybridizing Agents for
Wheat ( Triticum aestivum L.)
Not Available
 
Creator Chakraborty,Kajal
Devakumar,C
 
Subject Anilides
chemical hybridizing agents (CHAs)
QSAR
wheat
 
Description Not Available
Induction of male sterility by deployment of chemical hybridizing agents (CHAs) holds immense
potential in heterosis breeding of wheat. A total of 21 anilides having different aromatic substitutions
and side-chain variation were synthesized and screened as CHAs on three genotypes of wheat viz.,
PBW 343, HW 2046, and HD 2733, at winter season. Various anilides having vinyl moiety in the acyl
side chain were synthesized by condensation between substituted anilines with different esters or
acid chlorides. Another lead in the form of N-alkyl anilines also became evident. The percent male
sterility data caused by CHAs revealed the significant contribution of anilides containing vinyl double
bond incorporated in the form of closed ring structure viz., furyl moiety as the side chain. 4¢-Fluorofuryl
anilide (1) and 4¢-bromo-furyl anilide (2) are found to be promising lead CHAs for the design of
highly active molecules. QSAR analysis revealed a direct relationship of field effect exemplified by
the Swain-Lupton constant Fp for the aromatic substitution but an inverse relationship of molar
refractivity MR for the side chain. The negative influences of parachor for the acyl domain have been
underlined. The real guiding principle for selectivity of CHA action was found to be the ð value. The
CHAs act by mimicking UDP-glucose, the key substrate in the synthesis of callose, or lead to an
imbalance in acid-base equilibrium in pollen mother cells resulting in dissolution of callose wall by
premature callase secretion.
Not Available
 
Date 2021-09-08T06:28:50Z
2021-09-08T06:28:50Z
2005
 
Type Article
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/61627
 
Language English
 
Relation Not Available
 
Publisher American Chemical Society