Record Details

Virulence and intermediate resistance to high-end antibiotic (teicoplanin) among coagulase-negative staphylococci sourced from retail market fish

KRISHI: Publication and Data Inventory Repository

View Archive Info
 
 
Field Value
 
Title Virulence and intermediate resistance to high-end antibiotic (teicoplanin) among coagulase-negative staphylococci sourced from retail market fish
Not Available
 
Creator Muneeb, K. H.
Sudha, S.
Sivaraman, G. K.
Bibek Shome
Jennifer Cole
Mark Holmes
 
Subject Coagulase-negative staphylococci
Virulence genes
mecA gene
Type V SCCmec elements
Enterotoxins
 
Description Not Available
This study reports the distribution of enterotoxigenic determinants among staphylococci and the susceptibility of staphylococci to various classes of antibiotics. We observed all the isolates as resistant to beta-lactam antibiotics and a few as resistant to non-beta-lactam antibiotics such as clindamycin (47.4%), erythromycin (44.7%), gentamicin (23.7%), norfloxacin (34.2%), tetracycline (26.3%), trimethoprim-sulfamethoxazole (15.8%) etc. The resistance of S. sciuri (n = 1) and S. haemolyticus (n = 1) to rifampicin and intermediate resistance of S. gallinarum (n = 2) to teicoplanin, a high-end antibiotic, are also observed in this study. The multidrug-resistance (≥ 3 classes of antibiotics) was recorded in 23 (60.5%) isolates. The virulomes such as sea, seb, seg and sei were identified predominantly in S. haemolyticus. Surprisingly, certain isolates which were phenotypically confirmed as biofilm-producers by Congo red agar (CRA) test did not harbor biofilm-associated loci. This implies the protein-mediated mechanism of biofilm formation as an alternative to polysaccharide intercellular adhesin (PIA) in staphylococci. However, icaAD locus which encodes PIA was identified in 10 (26.3%) isolates and the eno locus, encoding elastin-binding protein which can accelerate the biofilm production, is identified in all the isolates. The possession of type V SCCmec elements by the S. haemolyticus (15.8%) raised the concern about the rapid dissemination of mecA gene to other species of staphylococci including the virulent S. aureus. In short, this study acknowledges the toxigenicity of coagulase-negative staphylococci (CoNS). Through this study, surveillance of antimicrobial resistance and transference of virulomes in staphylococci is warranted.
Not Available
 
Date 2022-04-11T05:31:06Z
2022-04-11T05:31:06Z
2021-09-01
 
Type Research Paper
 
Identifier Muneeb, K. H., Sudha, S., Sivaraman, G. K., Bibek Shome, Jennifer Cole and Mark Holmes (2021) Virulence and intermediate resistance to high-end antibiotic (teicoplanin) among coagulase-negative staphylococci sourced from retail market fish. Arch Microbiol. 203: 5695–5702.
0302-8933
http://krishi.icar.gov.in/jspui/handle/123456789/71363
 
Language English
 
Relation Not Available;
 
Publisher Springer