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Ameliorative effect of Chitosan-conjugated 17α-methyltestosterone on testicular development in Clarias batrachus

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Title Ameliorative effect of Chitosan-conjugated 17α-methyltestosterone on testicular development in Clarias batrachus
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Creator Saha, R., Bhat, I. A., Charan, R., Purayil, S. B. P., Krishna, G., Kumar, A. P., and Sharma, R*.
 
Subject Chitosan 17α-methyltestosterone Gonadosomatic index 11-ketotestosterone Spermatogenesis
 
Description Not Available
Chitosan nanoparticles conjugated with 17α-methyltestosterone (CS+MT) were used for
studying their effect on the testicular development of Clarias batrachus during different reproductive
phases. The size of chitosan nanoparticles was 127.2 nm and the nano-conjugated 17α
methyltestosterone (17α-MT) was 196.1 nm (20 mg/100 ml of chitosan). Single injections of
CS+MT at different doses such as 0.01, 0.1 and 0.5 μg/g body weight were administered to
adults during the pre-spawning, spawning and post-spawning phase. Nano-conjugated steroid
was effective at the lower dose; showing an increase in the Gonadosomatic Index (GSI) and 11-
ketotestosterone level compared to the control group. Histological observations confirmed the
dose-dependent advancement in spermatogenesis. These findings indicate the possibility of using
CS+MT for enhancing gonadal maturity of C. batrachus.
Not Available
 
Date 2022-06-15T10:50:42Z
2022-06-15T10:50:42Z
2018-04-12
 
Type Research Paper
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/72561
 
Language English
 
Relation Not Available;
 
Publisher ELSEVIER