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Expression analysis of Interleukin-1 receptor associated kinase-4 (irak-4) gene in midgut of lipopolysaccharide induced Penaeus monodon.

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Title Expression analysis of Interleukin-1 receptor associated kinase-4 (irak-4) gene in midgut of lipopolysaccharide induced Penaeus monodon.
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Creator Kumari R, Bedekar MK, Prasad KP, Kumar K, Rajendran KV
 
Subject Toll-like receptor (TLR), IRAK-4, LPS, P. monodon, gut immunity.
 
Description Not Available
ABSTRACT : Interleukin-1 receptor associated kinase-4 (IRAK-4) has been identified as a central signal transduction mediator of the Toll-like receptor (TLR) and Toll/interleukin-1 receptor (TIR) pathways both in vertebrate and invertebrate innate immunity. To investigate the role of Toll-pathway in innate immune response of shrimp, Penaeus
monodon, expression analysis of IRAK-4 gene in mid-gut of LPS induced shrimps wasdone at five time points. Responses of this gene to LPS by Quantitative real time PCR (qPCR) expression analysis of the IRAK-4 gene wasdone in control and LPS induced P. monodon. Mid-gut tissue expressions of theIRAK-4 gene was significantly up regulatedin the LPS induced group. The study indicatedthe critical role of IRAK-4 in gut immunityof P. monodon.
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Date 2022-06-17T06:13:02Z
2022-06-17T06:13:02Z
2019-06-01
 
Type Research Paper
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/72775
 
Language English
 
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Publisher Not Available