Physiological and molecular responses of a bottom dwelling carp, Cirrhinus mrigala to short-term environmental hypoxia.
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Title |
Physiological and molecular responses of a bottom dwelling carp, Cirrhinus mrigala to short-term environmental hypoxia.
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Creator |
Varghese T, Pal AK, Mishal P, Sahu NP, Dasgupta S
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Subject |
Physiological, dwelling carp, Cirrhinus mrigala, environmental hypoxia
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Description |
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An experiment was conducted to monitor temporal changes in the gene expression of a specific molecular marker, HIF-1a in response to a 15-day exposure to chronic hypoxia in a bottom dwelling carp, Cirrhinus mrigala. The expression level of HIF-1a mRNA was increased in gills of C. mrigala in response to 0.5 mg/L, dissolved oxygen (DO) for 15 days with the time of exposure, whereas it remained unchanged in fishes exposed to normoxia (DO, 6.5 mg/L). Based on the first experiment it is found that HIF is expressed at moderate level 72 hours, and it peaks at 7 and 15 days, indicating that 72 h is a tolerable time limit for survival under hypoxia for the particular species. Thus, a second experiment was conducted to evaluate the effect of hypoxia (0.5 mg/L) for 72 h and assessed different parameters such as metabolic enzymes, antioxidant enzymes and haematological parameters. The haematological parameters, such as RBC count, Hb and Hct values increased significantly (P Not Available |
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Date |
2022-06-20T04:18:04Z
2022-06-20T04:18:04Z 2017-08-01 |
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Type |
Research Paper
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Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/72984 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Research Gate
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