Protective Effect of Squalene against Isoproterenol-Induced Myocardial Infarction in Rats
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Title |
Protective Effect of Squalene against Isoproterenol-Induced Myocardial Infarction in Rats
Not Available |
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Creator |
Sabeena, K.H.
Anandan, R. Sankar, T. V. Viswanathan Nair, P. G. |
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Subject |
squalene
isoproterenol myocardial infarction lipid peroxidation mineral status membrane-bound ATPases |
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Description |
Not Available
The protective effect of squalene on membrane function and mineral status was examined in isoproterenol-induced myocardial infarction in male albino rats. The pretreatment with squalene at 2% level along with feed significantly reduced the isoproterenol-induced rise in the levels of plasma diagnostic marker enzymes. It counteracted isoproterenol-induced lipid peroxidation in plasma and heart tissue, and maintained the level of reduced glutathione in the heart tissue at near normalcy. Supplementation of squalene also exerted membrane stabilizing action against isoproterenol-induced myocardial infarction by maintaining the activities of membrane-bound ATPases in heart tissue and the mineral status (sodium, potassium and calcium) in plasma and heart tissue at near normal levels. The cardioprotective effect of squalene might be ascribable to its antioxidant nature and membrane stabilizing property. Not Available |
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Date |
2021-11-29T08:08:26Z
2021-11-29T08:08:26Z 2005 |
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Type |
Research Paper
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Identifier |
Sabeena, K.H., Anandan, R., Sankar, T. V. and Viswanathan Nair, P. G. (2005) Protective effect of squaline against Isoproterenol induced myocardial infraction in rats, J. Cli. Biochem.Nutr., 37(2): 55-60.
1880-5086 (Online) 0912-0009 (Print) http://krishi.icar.gov.in/jspui/handle/123456789/67963 |
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Language |
English
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Relation |
Not Available;
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Publisher |
J-stage
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