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Antifungal activity of the extractives of coleus forskohlii roots and Forskolin

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Title Antifungal activity of the extractives of coleus forskohlii roots and Forskolin
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Creator Eugene Sebastian J. Nidiry, Girija Ganeshan and A. N. Lokesha
 
Subject Coleus forskohlii, antifungal activity, Colletotrichum gloeosporioides, Alternaria solani, forskolin
 
Description Not Available
Hexane, ethyl acetate and methanol extractives of Coleus forskohlii roots exhibit mycelial growth inhibition of Colletotrichum gloeosporioides and spore germination inhibition of Alternaria solani. Forskolin, a diterpene present in C. forskohlii exhibit dose dependent spore germination inhibition of A. solani, this being the first report on the antifungal activity of this compound. Estimation of forskolin in the extractives by HPLC showed that while hexane extractive contained 3.9% forskolin and ethyl acetate extractive contained 4.6% forskolin, while the methanol extractive did not contain forskolin. The results clearly show that forskolin is one of the antifungal compounds present in the plant.
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Date 2019-10-15T04:47:01Z
2019-10-15T04:47:01Z
2015-12-01
 
Type Article
 
Identifier Not Available
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http://krishi.icar.gov.in/jspui/handle/123456789/23373
 
Language English
 
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Publisher Not Available