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<p>Facile and efficient one-pot multicomponent synthesis of a new class of substituted pyrimidine containing imidazoles catalyzed by ceric ammonium nitrate: Screening <em>in vitro</em> microbiological evaluation with various microorganisms</p>

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Title Statement <p>Facile and efficient one-pot multicomponent synthesis of a new class of substituted pyrimidine containing imidazoles catalyzed by ceric ammonium nitrate: Screening <em>in vitro</em> microbiological evaluation with various microorganisms</p>
 
Added Entry - Uncontrolled Name Rajeev, P V; Department of Chemistry, Hindustan Institute of Technology and Science, Chennai-600 016. Tamil Nadu, India
Begam, A K Ameerunisha; Department of Chemistry, Hindustan Institute of Technology and Science, Chennai-600 016. Tamil Nadu, India
Keerthana, R ; Department of Chemistry, Hindustan Institute of Technology and Science, Chennai-600 016. Tamil Nadu, India
Thanusu, J ; Department of Chemistry, Alpha College of Engineering, Chennai-600 124. Tamil Nadu, India
 
Uncontrolled Index Term Ceric ammonium nitrate, Imidazole, One-pot synthesis, Antimicrobial
 
Summary, etc. An effective and simple method for the one-pot synthesis of 4,6-diaryl-2-(2-aryl-4,5-diphenyl-1<em>H</em>-imidazol-1-yl)pyrimidines <strong>13-24</strong> from substituted 2-amino pyrimidine <strong>1-12</strong>, benzil, substituted aromatic aldehyde and ammonium acetate in methanol by using ceric ammonium nitrate (CAN) as catalyst has been described. This CAN catalyzed reactions are carried out at a temperature of 70-75°C and give very high yields in a lesser reaction time. All the synthesized compounds have been characterized by elemental analysis, FT-IR, <sup>1</sup>H NMR <sup>13</sup>C NMR and MS spectral data. All the newly synthesized compounds are tested for their <em>in vitro</em> antimicrobial activity against selected clinically isolated bacterial and fungal strains by disc diffusion and minimum inhibitory concentration method.
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-12-19 17:29:37
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJC/article/view/69479
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 12 (2022): Indian Journal of Chemistry-(IJC)
 
Language Note en