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Virus secret revealed: ribosome profiling uncovers unannotated translation initiation sites and hidden open-reading frame in the TYLCTHV genome

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Title Virus secret revealed: ribosome profiling uncovers unannotated translation initiation sites and hidden open-reading frame in the TYLCTHV genome
Not Available
 
Creator Kutubuddin A Molla
 
Subject Virus, Ribosome profiling, Translation, open-reading frame, Viral gene
 
Description Not Available
Viruses are too small to be seen in a light microscope, yet they cause havoc in plants as well as animal communities. In the midst of a viral pandemic, who would know better than us how much damage this tiny invisible foe can cause. Viruses need to produce numerous proteins for replication, movement, and pathogenesis. Having a tiny genome, viruses use non-conventional strategies like initiating protein synthesis from un-annotated sites to increase their coding capacity (Ho et al., 2021). Accurate annotation of viral genes is crucial to developing antiviral strategies. However, deciphering a full set of viral genes is a great challenge as viruses use hidden open-reading frames (ORFs) with unanticipated translation initiation sites (TISs).
Not Available
 
Date 2022-03-26T04:32:10Z
2022-03-26T04:32:10Z
2022-02-03
 
Type Review Paper
 
Identifier Kutubuddin A Molla, Virus secret revealed: ribosome profiling uncovers unannotated translation initiation sites and hidden open-reading frame in the TYLCTHV genome, The Plant Cell, 2022;, koac034, https://doi.org/10.1093/plcell/koac034
https://doi.org/10.1093/plcell/koac034
http://krishi.icar.gov.in/jspui/handle/123456789/70619
 
Language English
 
Relation Not Available;
 
Publisher Oxford University Press