Record Details

Is Marine ω-3 Long Chain Polyunsaturated Fatty Acids Intake, Natural Remedial Measure for Combating Global COVID-19 Pandemic? A Mini-Review

KRISHI: Publication and Data Inventory Repository

View Archive Info
 
 
Field Value
 
Title Is Marine ω-3 Long Chain Polyunsaturated Fatty Acids Intake, Natural Remedial Measure for Combating Global COVID-19 Pandemic? A Mini-Review
Not Available
 
Creator Anandan, R.
Jacob, M. R.
Fazil, T. S.
Ravishankar, C.N.
Suseela Mathew
 
Subject COVID-19
Docosahexaenoic acid
Eicosapentaenoic acid
ω-3 PUFA
Sardinella longiceps
 
Description Not Available
COVID-19 is considered as the most public health emergency of international concern and global scientific research is on fast track
to reduce the rise of epidemic curves. Marine natural bioactive molecules have been the starting point for the discovery of the
most important drugs. The marine oils rich in ω-3 long chain polyunsaturated fatty acids (ω - 3 LCPUFAs), especially,
eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are well known to exert promising human healthcare benefits such
as cardioprotective, antilipidemic, anti-inflammatory, anticancer, antiaging, antihypertensive, antidepression and antiarthritic
properties. Interestingly, the immunomodulatory and anti-inflammatory potential of ω - 3 LCPUFAs is capable of attenuating some
of the COVID-19 mediated pathophysiological abnormalities through inhibition of proinflammatory processes. Understanding the
basic mechanism of action of ω - 3 LCPUFAs on pathophysiological conditions associated with COVID - 19 may help address the
pandemic related healthcare complications. Classical mechanism of action of ω - 3 LCPUFAs in exhibiting anti-inflammatory
properties is probably through counteraction of nuclear factor - kB activation, which is a transcription factor potentially involved in
COVID-19 mediated of proinflammatory cytokine production. Also, dietary ω -3 LCPUFAs intake is well known to activate
generation of resolvins and protectin, which in turn can suppress COVID-19 associated inflammation responses. Considering the
beneficial actions of dietary intake of ω - 3 LCPUFAs rich marine oils, this mini-review elaborates the physiologic and metabolic
influences of ω -3 LCPUFAs on COVID-19 induced pathophysiological aberrations with relevance to their biochemical and molecular
functions.
Not Available
 
Date 2021-08-25T03:28:39Z
2021-08-25T03:28:39Z
2021-01
 
Type Research Paper
 
Identifier Anandan, R., Jacob, M. R., Fazil, T. S., Ravishankar, C. N. and Suseela Mathew (2021) Is Marine ω-3 Long Chain Polyunsaturated Fatty Acids Intake, Natural Remedial Measure for Combating Global COVID-19 Pandemic? A Mini-Review. SSR Inst. Int. J. Life Sci. 7(1): 2749-2753.
2581-8740 (Online) 2581-8732 (Print)
http://krishi.icar.gov.in/jspui/handle/123456789/60371
 
Language English
 
Relation Not Available;
 
Publisher Society for Scientific Research