ICAR Research Data Repository for Knowledge Management
Guaiane sesquiterpenes from seaweed Ulva fasciata Delile and their antibacterial properties
KRISHI: Publication and Data Inventory Repository
View Archive Info| Field | Value | |
| Title |
Guaiane sesquiterpenes from seaweed Ulva fasciata Delile and their antibacterial properties Not Available |
|
| Creator |
Chakraborty,Rekha D
Paulraj,R Lipton,A P Chakraborty,Kajal |
|
| Subject |
Ulva fasciata Delile
Guaiane sesquiterpenoides Antibacterial activity Minimum inhibitory concentration |
|
| Description |
Not Available
Two new guaiane sesquiterpene derivatives, guai-2-en-10a-ol (1) and guai-2-en-10a-methanol (2), were chromatographically purified as major constituents of the CHCl3/CH3OH (1:1, v/v) soluble fraction of Ulva fasciata. Acetylation of 2 furnished guai-2-en-10a-methyl methanoate (3) with acetyl group at C11 position. The structures of the compounds were elucidated using one and two-dimensional NMR and mass spectrometric analysis. Compounds 2 and 3 exhibited significant inhibition to the growth of Vibrio parahaemolyticus with minimum inhibitory concentrations of 25 and 35 mg/mL, respectively. The electronegative C10 acetyl group with high polarisability (7.02� 10�24 cm3) in 3 appeared to withdraw electron cloud from substituted cycloheptyl ring and (R)-3-methylcyclohept-1-ene moiety, thus acting as the nucleophilic center of the molecule resulting in high bioactivity. Not Available |
|
| Date |
2021-09-16T05:25:47Z
2021-09-16T05:25:47Z 2010 |
|
| Type |
Article
|
|
| Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/62620 |
|
| Language |
English
|
|
| Relation |
Not Available
|
|
| Publisher |
Elsevier
|
|