Sulphated galactopyran derived from Gracilaria opuntia, a marine macroalgae restores the antioxidant metabolic enzymes during STZ induced diabetic rats
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Title |
Sulphated galactopyran derived from Gracilaria opuntia, a marine macroalgae restores the antioxidant metabolic enzymes during STZ induced diabetic rats Not Available |
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Creator |
Makkar,Fasina
Anusree,M Chakraborty,Kajal Valluru,Lokanatha Lavanya,R |
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Subject |
Marine macroalgae Oxidative stress Antioxidants Streptozotocin Diabetes |
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Description |
Not Available
In vitro antioxidant assays of FM4 were estimated by DPPH, ABTS, hydroxyl free radical and Nitric oxide free radical activities. FM4 was purified and characterized by 1H-NMR spectra and FTIR as sulphated galactopyran. Diabetes was induced intraperitonially by single dose of STZ (55 mg/kg body weight). FM4 was administrated orally (80, 100, 125 mg/kg BW) to diabetic rats for 60 days. The enzymatic and non-enzymatic antioxidants such as superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), glutathione-S-transferase (GST), lipid peroxidase (LPx), glutathione reduced (GSH), vitamin-C (VIT-C) and vitamin-E (VIT-E) levels were estimated. Glibenclamide was used as standard drug. Not Available |
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Date |
2021-09-17T09:00:24Z
2021-09-17T09:00:24Z 2017 |
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Type |
Article
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Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/63979 |
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Language |
English
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Relation |
Not Available
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Publisher |
Not Available
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