Pharmacological properties of marine macroalgae-associated heterotrophic bacteria
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Title |
Pharmacological properties of marine macroalgae-associated heterotrophic bacteria Not Available |
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Creator |
Vinaya,K K
Chakraborty,Kajal |
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Subject |
Intertidal marine macroalgae
Heterotrophic bacteria Firmicutes Bacillus amyloliquefaciens MTCC 12716 Antibacterial Pharmacological properties Nuclear magnetic resonance-based fingerprinting |
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Description |
Not Available
The rich diversity of marine macroalgae and their associated bacterial flora represent a potential reservoir of bioactive compounds with valuable biotechnological and pharmaceutical use. Heterotrophic bacteria associated with the intertidal macroalgae were isolated and evaluated for their pharmacological properties using various in vitro models. Among 148 cultivable isolates, more than 50% were dominated by γ-Proteobacteria and Firmicutes, wherein 53 of them showed consistent antibacterial activity against a broad spectrum of clinically significant pathogens. The bacteria were characterized by extensive microbiological, molecular and chemical identification tools. The heterotrophs Bacillus amyloliquefaciens MTCC 12716 and Shewanella algae MTCC 12715 isolated from a red marine macroalga Hypnea valentiae exhibited potential anti-infective properties against multidrug-resistant pathogens, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis (minimum inhibitory concentration of 6.25–12.5 µg/mL). The organic extract of B. amyloliquefaciens displayed significantly greater antioxidative properties (IC90 0.8, P Not Available |
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Date |
2021-09-18T04:35:05Z
2021-09-18T04:35:05Z 2019 |
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Type |
Article
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Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/64314 |
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Language |
English
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Relation |
Not Available
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Publisher |
Not Available
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