Record Details

Pharmacological Properties of Seaweeds against Progressive Lifestyle Diseases

KRISHI: Publication and Data Inventory Repository

View Archive Info
 
 
Field Value
 
Title Pharmacological Properties of Seaweeds against Progressive
Lifestyle Diseases
Not Available
 
Creator Antony,Tima
Chakraborty,Kajal
 
Subject Seaweeds
pharmacological
properties
anti-diabetic
anti-inflammatory
anti-hypertensive
nuclear
magnetic resonance-guided
dereplication
 
Description Not Available
Seaweeds are consumed as staple food items in the cuisines of many Asian
countries and are considered as essential components of a healthy diet. The
pharmacological potential of ethyl acetate-methanol (EtOAc-MeOH) extract of
10 species of seaweeds belonging to the subclasses Dictyotophycidae,
Rhodymeniophycidae, and Corallinophycidae against progressive lifestyle diseaseswas
determined by various in vitro models. Among the studied species, the
organic extracts of Gracilaria salicornia and Padina tetrastromatica exhibited
potential dipeptidyl-peptidase-4 inhibiting activity (IC50 ~ 0.03 mg mL−1) and
angiotensin converting enzyme-I inhibitory property (ACE-I) (IC50 0.12 mg mL−1)
compared to those displayed by other studied species. The organic extracts of
G. salicornia and P. tetrastromatica also displayed significantly greater attenuation
properties against pro-inflammatory cyclooxygenase-2 and 5-lipoxygenase
(IC50 0.98–1.34 mg mL−1, P < .05) compared to those derived from other species
(IC50 1.99–5.02 mg mL−1). The nuclear magnetic resonance-guided dereplication
of organic extracts of the studied seaweed species recognized the co-linearity
between the bioactive potential and downfield electronegative functionalities.
These results recognized the significance of the organic extracts of G. salicornia
and P. tetrastromatica to isolate compounds for functional food applications
against oxidative stress and induced diseases, such as diabetes, hypertension,
and inflammation.
Not Available
 
Date 2021-09-18T04:35:05Z
2021-09-18T04:35:05Z
2019
 
Type Article
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/64315
 
Language English
 
Relation Not Available
 
Publisher Elsevier