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Wide Horizons of CRISPR-Cas-Derived Technologies for Basic Biology, Agriculture, and Medicine

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Title Wide Horizons of CRISPR-Cas-Derived Technologies for Basic Biology, Agriculture, and Medicine
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Creator Kutubuddin A. Molla Subhasis Karmakar M. Tofazzal Islam
 
Subject Basic Biology, CRISPR-Cas, Agriculture, Medicine
 
Description Not Available
The discovery and subsequent repurposing of the CRISPR (clustered regularly interspaced short palindromic repeats) and Cas proteins (CRISPR-associated proteins) has revolutionized our ability to manipulate DNA and RNA sequences in vitro, ex vivo, and in vivo. In this introductory chapter, we present a brief overview of basics of CRISPR-Cas-mediated genome editing and different orthologues and engineered versions of Cas protein with altered specificity and expanded targetability. More importantly, we comprehensively portray the advances made by developing diverse CRISPR-Cas-based genome modification tools and their application in basic biology, agriculture, and medicine.
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Date 2021-01-01T12:11:44Z
2021-01-01T12:11:44Z
2020-07-01
 
Type Book
 
Identifier https://doi.org/10.1007/978-1-0716-0616-2_1
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http://krishi.icar.gov.in/jspui/handle/123456789/44430
 
Language English
 
Relation Not Available;
 
Publisher Springer