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Psoriasis Vrs Cassia Fistula: In-Silico Study

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Title Psoriasis Vrs Cassia Fistula: In-Silico Study
Not Available
 
Creator Chandra Sekhar Tripathy
Anil Kumar
Ghassem Habibi Bibalani
Santosh Kumar Behera
Santanu Kumar Budhia
P K Mohanta
Easter Khura
Asadollah Asadi
Arash Abdolmaleki
Muhammad Akram
Debasish Mishra
Deepak Bhattacharya
 
Subject Psoriasis
TRPV3 ion channel
Cassia fistula
Molecular docking
in silico study
 
Description Not Available
Psoriasis is a skin disease. It is rare growing disease around the world. Here in this investigation we have targeted a
protein namely TRPV3 (Transient receptor potential cation channel, subfamily III) ion channel for the study of psoriasis,
which is important factor of psoriasis. The medicinal plant namely Cassia fistula is selected for the in silico investigation.
39 phyto compounds as reported in various research papers are taken for study. Out of 39 phytochemicals, Chrysophanol
compound showed highest binding affinity of -7.58kcal/mol having 3 conventional Hydrogen bonds with TRPV3 protein
and is found to be a better natural compound as compared to other reported drugs generally used to for the psoriasis. This
investigation will lead to more and better findings leading to drug discovery & use as functional food.
Not Available
 
Date 2022-03-30T09:39:32Z
2022-03-30T09:39:32Z
2022-03-22
 
Type Research Paper
 
Identifier Chandra Sekhar Tripathy, Anil Kumar, Ghassem Habibi Bibalani , Santosh Kumar Behera , Santanu Kumar Budhia , P K Mohanta , Easter Khura, Asadollah Asadi , Arash Abdolmaleki , Prof. Muhammad Akram , Debasish Mishra , Deepak Bhattacharya (2021). Psoriasis Vrs Cassia Fistula: In-Silico Study , Saudi Journal of Medicine, DOI: 10.36348/sjm.2022.v07i03.005
2518-3389 (Print)
2518-3397 (Online)
http://krishi.icar.gov.in/jspui/handle/123456789/70915
 
Language English
 
Relation Not Available;
 
Publisher Not Available