Psoriasis Vrs Cassia Fistula: In-Silico Study
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Title |
Psoriasis Vrs Cassia Fistula: In-Silico Study
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Creator |
Chandra Sekhar Tripathy
Anil Kumar Ghassem Habibi Bibalani Santosh Kumar Behera Santanu Kumar Budhia P K Mohanta Easter Khura Asadollah Asadi Arash Abdolmaleki Muhammad Akram Debasish Mishra Deepak Bhattacharya |
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Subject |
Psoriasis
TRPV3 ion channel Cassia fistula Molecular docking in silico study |
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Description |
Not Available
Psoriasis is a skin disease. It is rare growing disease around the world. Here in this investigation we have targeted a protein namely TRPV3 (Transient receptor potential cation channel, subfamily III) ion channel for the study of psoriasis, which is important factor of psoriasis. The medicinal plant namely Cassia fistula is selected for the in silico investigation. 39 phyto compounds as reported in various research papers are taken for study. Out of 39 phytochemicals, Chrysophanol compound showed highest binding affinity of -7.58kcal/mol having 3 conventional Hydrogen bonds with TRPV3 protein and is found to be a better natural compound as compared to other reported drugs generally used to for the psoriasis. This investigation will lead to more and better findings leading to drug discovery & use as functional food. Not Available |
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Date |
2022-03-30T09:39:32Z
2022-03-30T09:39:32Z 2022-03-22 |
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Type |
Research Paper
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Identifier |
Chandra Sekhar Tripathy, Anil Kumar, Ghassem Habibi Bibalani , Santosh Kumar Behera , Santanu Kumar Budhia , P K Mohanta , Easter Khura, Asadollah Asadi , Arash Abdolmaleki , Prof. Muhammad Akram , Debasish Mishra , Deepak Bhattacharya (2021). Psoriasis Vrs Cassia Fistula: In-Silico Study , Saudi Journal of Medicine, DOI: 10.36348/sjm.2022.v07i03.005
2518-3389 (Print) 2518-3397 (Online) http://krishi.icar.gov.in/jspui/handle/123456789/70915 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Not Available
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