Identification of Potential Cytokinin Responsive Key Genes in Rice treated with trans-zeatin through Systems Biology Approach
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Title |
Identification of Potential Cytokinin Responsive Key Genes in Rice treated with trans-zeatin through Systems Biology Approach
Not Available |
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Creator |
Mishra Dwijesh Chandra
Arora Devender Budhlakoti Neeraj Solanke Amolkumar U Sevanthi Amitha Mithra V Kumar Anuj Pandey PS Srivastava Sudhir Kumar Sanjeev Farooqi M S Lal Shashi Bhushan Rai Anil K. K. Chaturvedi |
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Subject |
WGCNA
systems biology co-expression cytokinin hub genes QTLs |
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Description |
Not Available
Rice is an important staple food grain consumed by most of the population around the world. With climate and environmental changes, rice has undergone a tremendous stress state which has impacted crop production and productivity. Plant growth hormones are essential component that controls the overall outcome of the growth and development of the plant. Cytokinin is a hormone that plays an important role in plant immunity and defense systems. Trans-zeatin is an active form of cytokinin that can affect plant growth which is mediated by a multi-step two-component phosphorelay system that has different roles in various developmental stages. Systems biology is an approach for pathway analysis to trans-zeatin treated rice that could provide a deep understanding of different molecules associated with them. In this study, we have used a weighted gene co-expression network analysis method to identify the functional modules and hub genes involved in the cytokinin pathway. We have identified nine functional modules comprising of different hub genes which contribute to the cytokinin signaling route. The biological significance of these identified hub genes has been tested by applying well-proven statistical techniques to establish the association with the experimentally validated QTLs and annotated by the DAVID server. The establishment of key genes in different pathways has been confirmed. These results will be useful to design new stress-resistant cultivars which can provide sustainable yield in stress-specific conditions. Not Available |
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Date |
2022-04-19T07:35:07Z
2022-04-19T07:35:07Z 2022-02-07 |
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Type |
Research Paper
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Identifier |
Mishra Dwijesh Chandra, Arora Devender, Budhlakoti Neeraj, Solanke Amolkumar U., Mithra S. V. Amitha CR, Kumar Anuj, Pandey P. S., Srivastava Sudhir, Kumar Sanjeev, Farooqi M. S., Lal S. B., Rai Anil, Chaturvedi K. K.(2022). Identification of Potential Cytokinin Responsive Key Genes in Rice Treated With Trans-Zeatin Through Systems Biology Approach, Frontiers in Genetics, 12.
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/71625 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Not Available
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