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HRE Finder: A Tool for Quarrying Hypoxia-Response Element in Genomic Sequences

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Title HRE Finder: A Tool for Quarrying Hypoxia-Response Element in Genomic Sequences
Not Available
 
Creator Iliyas, R.
N.S. Nagpure
P. Srivastava
A.K. Pathak
R. Kumar
V. S. Baisvar
M. Singh
B. Kushwaha
 
Subject Database
Hypoxia inducible factor
Hypoxia response element
Hypoxia
Transcription
Gene
Enhancer
Search algorithm
 
Description Not Available
During hypoxia, the hypoxia inducible factor (HIF) binds to hypoxia-response elements (HRE) and induces the expression of hypoxia-inducible genes (HIG). A functionally active HRE typically contains an adjacent hypoxia ancillary sequence (HAS) in its downstream within the space of 7-15 nt. Here, a computational tool 'HRE Finder' is discussed using an example data set. The tool provides the ability for mining canonical HREs and predicting functional HREs in the upstream region of genes, which can be an indispensable tool for genome-wide analysis and identification of hypoxia inducible genes in vertebrates.
CABin, ICAR-IASRI, New Delhi.
 
Date 2021-07-23T06:14:46Z
2021-07-23T06:14:46Z
2017-07-10
 
Type Research Paper
 
Identifier Iliyas Rashid, Naresh Sahebrao Nagpure, Prachi Srivastava, Ajey Kumar Pathak, Ravindra Kumar, Vishwamitra Singh Baisvar, Mahender Singh and Basdeo Kushwaha. 2017. HRE Finder: A Tool for Quarrying Hypoxia-Response Element in Genomic Sequences.Int.J.Curr.Microbiol.App.Sci. 6(7): 1580-1586. doi: https://doi.org/10.20546/ijcmas.2017.607.190
2319-7706
http://krishi.icar.gov.in/jspui/handle/123456789/49460
 
Language English
 
Relation Not Available;
 
Publisher Excellent Publishers