Pectin induced transcriptome of a Rhizoctonia solani strain causing sheath blight disease in rice reveals insights on key genes and RNAi machinery for development of pathogen derived resistance
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Title |
Pectin induced transcriptome of a Rhizoctonia solani strain causing sheath blight disease in rice reveals insights on key genes and RNAi machinery for development of pathogen derived resistance
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Creator |
Bhaskar Rao T, Chopperla R, Methre R, Punniakoti E, Venkatesh V, Sailaja B, Reddy MR, Yugander A, Laha GS, Madhav MS, Sundaram RM, Ladhalakshmi D, Balachandran SM and Mangrauthia SK
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Subject |
Oryza sativa
Polygalacturonase Transgenic RNAseq Silencing |
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Description |
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Rice sheath blight disease caused by Rhizoctonia solani Kuhn (telemorph; Thanatephorus cucumeris) is one of the most devastating fungal diseases which cause severe loss to rice grain production. In the absence of resistant cultivars, the disease is currently managed through fungicides which add to environmental pollution. To explore the potential of utilizing RNA interference (RNAi)-mediated resistance against sheath blight disease, we identified genes encoding proteins and enzymes involved in the RNAi pathway in this fungal pathogen. The RNAi target genes were deciphered by RNAseq analysis of a highly virulent strain of the R. solani grown in pectin medium. Additionally, pectin metabolism associated genes of R. solani were analyzed through transcriptome sequencing of infected rice tissues obtained from six diverse rice cultivars. One of the key candidate gene AG1IA_04727 encoding polygalacturonase (PG), which was observed to be significantly upregulated during infection, was targeted through RNAi to develop disease resistance. Stable expression of PG-RNAi construct in rice showed efficient silencing of AG1IA_04727 and suppression of sheath blight disease. This study highlights important information about the existence of RNAi machinery and key genes of R. solani which can be targeted through RNAi to develop pathogen-derived resistance, thus opening an alternative strategy for developing sheath blight-resistant rice cultivars. Department of Biotechnology, Government of India Grant no BT/ PR6466/COE/34/16/2012 |
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Date |
2021-08-03T08:27:58Z
2021-08-03T08:27:58Z 2019-02-22 |
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Type |
Research Paper
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Identifier |
Rao, T.B., Chopperla, R., Methre, R. et al. Pectin induced transcriptome of a Rhizoctonia solani strain causing sheath blight disease in rice reveals insights on key genes and RNAi machinery for development of pathogen derived resistance. Plant Mol Biol 100, 59–71 (2019). https://doi.org/10.1007/s11103-019-00843-9
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/52559 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Not Available
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