MAPK cascade gene family in Camellia sinensis: In-silico identification, expression profiles and regulatory network analysis
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Title |
MAPK cascade gene family in Camellia sinensis: In-silico identification, expression profiles and regulatory network analysis
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Creator |
Chatterjee, Archita
Paul, Abhirup Unnati, G. Meher Rajput, Ruchika Biswas, Trisha Kar, Tamalika Basak, Srijita Mishra, Neelam Pandey, Ashutosh Srivastava, Anurag Prakash |
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Subject |
Camellia sinensis
MAPK cascade Expression profile Functional interaction network In-silico |
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Description |
Accepted date: 27 August 2020
Background: Mitogen Activated Protein Kinase (MAPK) cascade is a fundamental pathway in organisms for signal transduction. Though it is well characterized in various plants, there is no systematic study of this cascade in tea. Result: In this study, 5 genes of Mitogen Activated Protein Kinase Kinase (MKK) and 16 genes of Mitogen Activated Protein Kinase (MPK) in Camellia sinensis were found through a genome-wide search taking Arabidopsis thaliana as the reference genome. Also, phylogenetic relationships along with structural analysis which includes gene structure, location as well as protein conserved motifs and domains, were systematically examined and further, predictions were validated by the results. The plant species taken for comparative study clearly displayed segmental duplication, which was a significant candidate for MAPK cascade expansion. Also, functional interaction was carried out in C. sinensis based on the orthologous genes in Arabidopsis. The expression profiles linked to various stress treatments revealed wide involvement of MAPK and MAPKK genes from Tea in response to various abiotic factors. In addition, the expression of these genes was analysed in various tissues. Conclusion: This study provides the targets for further comprehensive identification, functional study, and also contributed for a better understanding of the MAPK cascade regulatory network in C. sinensis. This work was supported by the core grant of National Institute of Plant Genome Research and Indian National Science Academy (INSA), New Delhi for Young Scientist Research Grant (Sanction No. SP/YSP/150/2018/231) to A.P2. |
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Date |
2020-09-10T05:49:34Z
2020-09-10T05:49:34Z 2020 |
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Type |
Article
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Identifier |
BMC Genomics, 21: 613
1471-2164 https://doi.org/10.1186/s12864-020-07030-x https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-020-07030-x http://223.31.159.10:8080/jspui/handle/123456789/1095 |
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Language |
en_US
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Format |
application/pdf
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Publisher |
BioMed Central Ltd
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