Record Details

Unreported bis-abeo cembrane-type diterpenoid with antioxidative and anti-lipoxygenase activities from the muricid gastropod mollusc Chicoreus ramosus

CMFRI Repository

View Archive Info
 
 
Field Value
 
Relation http://eprints.cmfri.org.in/15895/
https://www.tandfonline.com/doi/full/10.1080/14786419.2018.1527833
/doi.org/10.1080/14786419.2018.1527833
 
Title Unreported bis-abeo cembrane-type diterpenoid with antioxidative and anti-lipoxygenase activities from the muricid gastropod mollusc Chicoreus ramosus
 
Creator Chakraborty, Kajal
Salas, Soumya
Joy, Minju
 
Subject Bioactive compounds
Gastropods
Fish Biotechnology
Molluscan Fisheries
 
Description The chemical analyses of ethyl acetate-methanol (EtOAc-MeOH) extract of muricid gastropod mollusk, Chicoreus ramosus from the southeastern coast of Indian peninsular led to the identification of unprecedented cembrane-type diterpenoid, which was characterized as (3E, 6E, 10E)-8a-butoxy-17(15→14), 20(12→11)-bis-abeo-cembra-3,6,10,14(17),15-pentaene (1). The structure of the studied cembrane was unambiguously assigned through the extensive spectroscopic experimentations. The antioxidant potentials of the bis-abeo cembrane as determined by in vitro 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis-3-ethylbenzothiozoline-6-sulfonic acid diammonium salt radical quenching potentials were greater (IC50  0.60 mg/mL). The pro-inflammatory anti-5-lipoxygenase potential of studied cembrane was higher (IC50  0.90 mg/mL).
 
Publisher Taylor and Francis
 
Date 2020
 
Type Article
PeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/15895/1/Natural%20Product%20Research_2020_Kajal%20Chakraborty.pdf
Chakraborty, Kajal and Salas, Soumya and Joy, Minju (2020) Unreported bis-abeo cembrane-type diterpenoid with antioxidative and anti-lipoxygenase activities from the muricid gastropod mollusc Chicoreus ramosus. Natural Product Research, 34 (12). pp. 1-10. ISSN 1478-6427 (Online)