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Effect of exogenous bovine somatotropin on the blood serum protein profile in lactating crossbred cows*

Indian Agricultural Research Journals

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Title Effect of exogenous bovine somatotropin on the blood serum protein profile in lactating crossbred cows*
 
Creator BHARUCHA, S V
DESHMUKH, B T
NAGVEKAR, A S
TALVELKAR, B A
 
Subject Blood serum protein profile, Exogenous bovine somatotropin, Lactating cows, Somatotropin
 
Description Apparently healthy multiparous crossbred cOfs (24), based on milk production and parity were randomly allocated to 4 treatment groups to study the effect of exogenous bovine somatotropin on the serum protein profile in lactating crossbred cows. The treatments were control and 3 dose rates of 250, 350 and 500 mg sometribove zinc suspension in a sustained release preparation. Sometribove is a sterile prolonged release injectable formulation of a recombinant DNA derivcd bovine somatotropin. Cows in the control group received placebo injections of normal saline. Treatments were initiated at 55 to 92 days postpartum and continued for 140 days. The injections were administered subcutaneously in the area between the pins and tail head (ischiorectal fossa), alternately on the left/right side. at every 14 days interval. for 10 injection cycles. The blood samples were collected on the second day of sometribove injection. Administration of bovine somatotropin did not affect the serum total proteins, albumin and blood urea nitrogen concentrations, which remained almost similar in treated and control groups. The serum creatinine and total immunoglobulins concentrations were not affected except in the group treated with 250 mg sometribove for creatinine, and in the group treated with 350 mg sometribove for total immunoglobulins, which in these groups were higher. The serum globulin concentration was not affected except in the group treated with 250 mg sometribove which in this group was lower.
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor
 
Date 2014-01-21
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/36870
 
Source The Indian Journal of Animal Sciences; Vol 71, No 7 (2001)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/36870/16459
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences