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Effect of pesticides on delayed type hypersensitivity reaction in sheep

Indian Agricultural Research Journals

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Title Effect of pesticides on delayed type hypersensitivity reaction in sheep
 
Creator Khurana, Rajesh
Mahipal, S K
Chauhan, R S
 
Subject Dinitrofluorobenzene; Immunotoxic effect; Lambs; Pesticides
 
Description lmmunotoxic effect of lindane, monocrotophos, carbofuran and fenvalerate on cell-mediated immune response was measured by delayed type hypersensitivity (DTH) reaction in sheep using dinitrofluorobenzene (DNFB) as antigen, The pesticides were given orally for 6 month daily @ 1.25 ppm lindane, 0.025 ppm monoerotophos, 2.5 ppm carbofuran and 1.25 ppm fenvalcrate to 4 lambs each. All the pesticides caused suppression of cell-mediated immune response as indicated by significant reduction in DTH reaction in pesticide-treated groups, The reduction was more at 24 and 36 hr after challenge with DNFB. On histopathological examination, the skin of pesticide fed lambs showed mild mononuclear infiltration.
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2012-07-18
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/21375
 
Source The Indian Journal of Animal Sciences; Vol 69, No 11 (1999)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/21375/10813
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences