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Pharmacological potential of seaweed-associated heterotrophic Firmicutes

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Relation http://eprints.cmfri.org.in/16065/
https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/lam.13780
https://doi.org/10.1111/lam.13780
 
Title Pharmacological potential of seaweed-associated heterotrophic Firmicutes
 
Creator Asharaf, Sumayya
Chakraborty, Kajal
 
Subject Seaweed
 
Description Seaweed-associated bacterial symbionts are sources of potential pharmacological properties. The present study resulted in the culture-dependent isolation of bioactive heterotrophs belonging to the bacterial phylum Firmicutes, which were dominated more than 30% of the 127 cultivable isolates, amongst which 23 of them showed potential antimicrobial activities against a wide range of pathogens. The symbionts isolated from the seaweed Sargassum wightii showed significant bioactivity. Those were characterized as Bacillus safensis MTCC13040, B. valismortis MTCC13041, B. velezensis MTCC13044, B. methylotrophicus MTCC13042, Oceanobacillus profundus MTCC13045, B. tequilensis MTCC13043, and B. altitudinis MTCC13046. The organic extracts of the studied isolates showed potential antimicrobial properties against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci (minimum inhibitory concentration 6·25–12·5 μg ml−1). The organic extract of B. altitudinis MTCC13046 displayed significantly greater radical quenching ability (IC90 133 μg ml−1, P 
 
Publisher Society for Applied Microbiology
 
Date 2022
 
Type Article
PeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/16065/1/Letters%20in%20Applied%20Microbiology_2022_Kajal%20Chakraborty.pdf
Asharaf, Sumayya and Chakraborty, Kajal (2022) Pharmacological potential of seaweed-associated heterotrophic Firmicutes. Letters in Applied Microbiology. pp. 1-13. ISSN 0266-8254