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Pharmacological properties of marine macroalgae-associated heterotrophic bacteria

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Relation http://eprints.cmfri.org.in/13649/
https://link.springer.com/article/10.1007%2Fs00203-018-1592-1
https://doi.org/10.1007/s00203-018-1592-1
 
Title Pharmacological properties of marine macroalgae-associated
heterotrophic bacteria
 
Creator Vinaya, K K
Chakraborty, Kajal
 
Subject Bioactive compound
Biochemistry
Fish Biotechnology
Algae
 
Description The rich diversity of marine macroalgae and their associated bacterial flora represent a potential reservoir of bioactive compounds with valuable biotechnological and pharmaceutical use. Heterotrophic bacteria associated with the intertidal macroalgae were isolated and evaluated for their pharmacological properties using various in vitro models. Among 148 cultivable isolates, more than 50% were dominated by γ-Proteobacteria and Firmicutes, wherein 53 of them showed consistent antibacterial activity against a broad spectrum of clinically significant pathogens. The bacteria were characterized by extensive microbiological, molecular and chemical identification tools. The heterotrophs Bacillus amyloliquefaciens MTCC 12716 and Shewanella algae MTCC 12715 isolated from a red marine macroalga Hypnea valentiae exhibited potential anti-infective properties against multidrug-resistant pathogens, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis (minimum inhibitory concentration of 6.25–12.5 µg/mL). The organic extract of B. amyloliquefaciens displayed significantly greater antioxidative properties (IC90  0.8, P 
 
Date 2019
 
Type Article
PeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/13649/1/Archives%20of%20Microbiology_2019_Kajal%20Chakraborty_Pharmacological%20properties%20of%20marine%20macroalgae-associated%20heterotrophic%20bacteria.pdf
Vinaya, K K and Chakraborty, Kajal (2019) Pharmacological properties of marine macroalgae-associated heterotrophic bacteria. Archives of Microbiology, 201 (4). pp. 505-518.