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Synthesis, characterization and antimicrobial studies of (E)-N-((2-chloro-6- substituted quinolin-3-yl)methylene)-4-(substituted phenyl)-6-phenyl-2H-1,3- oxazin-2-amines

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Title Synthesis, characterization and antimicrobial studies of (E)-N-((2-chloro-6- substituted quinolin-3-yl)methylene)-4-(substituted phenyl)-6-phenyl-2H-1,3- oxazin-2-amines
 
Creator P, Dayananda
Nayak, Janardhana
D’Souza, Vineetha Telma
 
Subject Quinoline
Oxazine
Spectroscopy
Antibacterial
Antifungal
 
Description 49-52
Research work is planned to synthesize novel (E)-N-((2-chloro-6-substituted quinolin-3-yl)methylene)-4-(substituted
phenyl)-6-phenyl-2H-1,3-oxazin-2-amines by the reaction of 6-(3-substituted phenyl)-4-(4-substituted phenyl)-5,6-dihydro-
4H-1,3-oxazin-2-amines with 6-substituted-2-chloro-quinoline-3-carbaldehydes in alcoholic medium and in the presence of
acetic acid. The structures of synthesized compounds are assigned on the basis of FT-IR, 1H-NMR, 13C-NMR and Mass
spectral data. The new compounds are also screened for their antibacterial and antifungal activities. These compounds are
showing potent antimicrobial activities due to their chemical structure.
 
Date 2023-01-18T10:46:53Z
2023-01-18T10:46:53Z
2023-01
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61215
https://doi.org/10.56042/ijc.v62i1.70392
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.62(01) [Jan 2023]