Genome-Wide Association Study for Major Biofuel Traits in Sorghum Using Minicore Collection
OAR@ICRISAT
View Archive InfoField | Value | |
Relation |
http://oar.icrisat.org/12042/
http://dx.doi.org/10.2174/0929866528666210215141243 |
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Title |
Genome-Wide Association Study for Major Biofuel Traits in Sorghum Using Minicore Collection
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Creator |
Rayaprolu, L
Selvanayagam, S Rao, D M Gupta, R Das, R R Rathore, A Gandham, P Kiranmayee, K N S U Deshpande, S P Are, A K |
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Subject |
Biofuels
Sorghum Others |
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Description |
Background: Production of biofuels from lignocellulosic crop biomass is an alternative to reduce greenhouse gas emissions. The biofuel production involves collecting biomass, breaking down cell wall components followed by the conversion of sugars to ethanol. The lingo-cellulosic biomass comprises 40-50% cellulose, 20-30% hemicellulose, and 10-25% lignin. Sorghum is a widely adapted energy crop for biofuel production. Biomass with low lignin, high cellulose, and high hemicellulose contents are exploited to attain maximum biofuel production efficiency. Resistance to lodging, pest, disease, and abiotic stresses related to cell wall components is well documented, and quantitative trait loci were identified to understand these traits' genetic correlation. Selection for reduced lignin and increased cellulose content in stover can increase the ethanol yield. The Genome-Wide Association Studies (GWAS) is a complementary approach to evaluating the marker and phenotype associations among large diversity panels. Single nucleotide polymorphisms were scanned to identify loci associated with the traits of interest. In this study, the GWAS was performed on 245 sorghum minicore genotypes to analyze agronomic traits (days to 50%flowering, fresh biomass yield, dry biomass yield) and cell wall components (cellulose, hemicellulose, and lignin). Further, in-silico validation of the candidate genes was performed in a global gene expression data from large-scale RNA sequencing studies in sorghum available in the NCBI GEO database was used. Objective: The objectives of this study are to evaluate native variations in biofuel related agronomic traits and stalk cell wall components and to identify significant SNPs or loci related to the cell wall components. Methods: In this article, an association mapping panel, comprising of 245 sorghum minicore germplasm accessions, was evaluated during two post rainy seasons of 2013 and 2014, and observations were recorded on the whole plot- for days to 50% flowering, fresh biomass yield (tha-1), and dry biomass yield (tha-1). The biomass of sun-dried plants from both seasons was collected separately, chopped, dried, and ground to powder. The cellulose, hemicellulose, and lignin contents were determined in the powdered. The content of each of these three components in sorghum was expressed in percent of dry matter. The data on agronomic traits and composition analysis was subjected to Analysis of Variance. For the current study, we remapped the raw GBS data with the sorghum assembly version v3.1. A total of 27,589 SNPs were obtained with a minor allele frequency (MAF) >1% and missing data |
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Publisher |
BENTHAM SCIENCE PUBL LTD
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Date |
2021-01-08
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Type |
Article
PeerReviewed |
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Identifier |
Rayaprolu, L and Selvanayagam, S and Rao, D M and Gupta, R and Das, R R and Rathore, A and Gandham, P and Kiranmayee, K N S U and Deshpande, S P and Are, A K (2021) Genome-Wide Association Study for Major Biofuel Traits in Sorghum Using Minicore Collection. Protein & Peptide Letters (TSI), 28 (8). pp. 909-928. ISSN 1875-5305
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