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<p>Synthesis, characterization and fungicidal activity of novel 2-aminopyrimidine Schiff bases</p>

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Title Statement <p>Synthesis, characterization and fungicidal activity of novel 2-aminopyrimidine Schiff bases</p>
 
Added Entry - Uncontrolled Name Kaur, Amanpreet ; Department of Chemistry, Punjab Agricultural University, Ludhiana-141 004, Punjab, India
Sharma, Sunita ; Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana-141 004, Punjab, India
Verma, Diksha ; Department of Chemistry, Punjab Agricultural University, Ludhiana-141 004, Punjab, India
Sahni, Tanvi ; Department of Chemistry, Punjab Agricultural University, Ludhiana-141 004, Punjab, India
Kaur, Sukhmanpreet ; Department of Chemistry, Punjab Agricultural University, Ludhiana-141 004, Punjab, India
 
Uncontrolled Index Term 2-aminopyrimidine, Schiff base, Aromatic aldehydes, Conventional and microwave method, Antifungal activity
 
Summary, etc. <p style="text-align: justify;">2-Aminopyrimidines represents vital class of bioactive molecules where its structural changes would lead to its peculiar properties.<em> N</em>-heterocyclic compound i.e. 2-aminopyrimidine had wide range of applications in pharmacological, material chemistry and agriculture as antifungal, antimicrobial and antibacterial agents. 2-Aminopyrimidine and its derivatives are good candidates for antimicrobial, antifungal and anticorrosion activity. In the present study, a series of substituted <em>N</em>-benzylidine-2-aminopyrimidine compounds have been synthesized by condensation reaction of 2-aminopyrimidine with substituted benzaldehydes (<em>o</em>-chloro<em>, m</em>-hydroxybenzaldehyde, <em>p</em>-hydroxybenzaldehyde, 2,5-dimethoxybenzaldehyde, <em>p</em>-dimethylaminobenzaldehye, syringaldehyde, <em>o</em>-phthaldehyde, isovanillin benzaldehyde, veratraldehyde and thiophene-2-carboxyaldehyde) using glacial acetic acid or NaOH (40%). The synthesised Schiff bases have been characterized using UV, IR, <sup>1</sup>H NMR and <sup>13</sup>C spectral studies. 2-Aminopyrimidine Schiff bases (<strong>1-10</strong>) have been examined for fungitoxicity on the growth <em>of </em><em>Fusarium verticillioides</em>, <em>Rhizoctonia solani and Macrophomina phaseolina</em> using poisoned food technique.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2023-01-19 15:48:46
 
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http://op.niscair.res.in/index.php/IJC/article/view/70390
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 62, ##issue.no## 1 (2023): Indian Journal of Chemistry-(IJC)
 
Language Note en