Record Details

Influence of Eimeria maxima coccidia infection on gut microbiome diversity and composition of the jejunum and cecum of indigenous chicken

CGSpace

View Archive Info
 
 
Field Value
 
Title Influence of Eimeria maxima coccidia infection on gut microbiome diversity and composition of the jejunum and cecum of indigenous chicken
 
Creator Jebessa, Endashaw
Guo, L.
Chen, X.
Bello, S.F.
Cai, B.
Girma, Mekonnen
Hanotte, Olivier H.
Nie, Q.
 
Subject poultry
animal diseases
chickens
Eimeria maxima
indigenous breeds
 
Description Coccidiosis is an economically significant protozoan disease and an intracellular parasite that significantly impacts poultry production. The gastrointestinal tract microbiota plays a central role in host health and metabolism, and these microbes enhance chickens’ immune systems and nutrient absorption. In this study, we analyzed the abundance and diversity of microbiota of the jejunum and cecum of a dual-purpose indigenous Horro chicken following Eimeria maxima infection. We compared microbial abundance, composition, and diversity at the 4- and 7- days post-infection using 16S rRNA gene sequencing. We obtained, on average, 147,742 and 132,986 high-quality sequences per sample for jejunum and cecum content, respectively. Firmicutes, Proteobacteria, Campilobacterota and Bacteroidota were the major microbial phylum detected in the jejunum content. Firmicutes were the dominant phylum for 4- and 7-days jejunum control groups accounting for (>60% of the sequences). In the infected group Campilobacterota was the dominant phylum in the jejunum (> 24% of sequences) at 4-and 7-days post-infection groups, while Proteobacteria was predominant at 4- and 7-days post-infection of the cecum (> 40% of the sequences). The microbial genus Lactobacillus and Helicobacter were found in the jejunum, while Alistipes, Barnesiella and Faecalibacterium were detected in the cecum. In the jejunum, Helicobacter was dominant at 4 -and-7 days post-infection (≥24%), and Lactobacillus was dominant at 4 -and 7- days in the control group (> 50%). In 4- and 7-days post-infection, Alistipes genus was the more prevalent (> 38%) in the cecum. Thus, clear differences were observed in the bacterial microbiota distribution and abundance between the jejunum and cecum, as well as between infected and control groups for both tissues. The results indicate that chicken intestinal microbial imbalance (dysbiosis) is associated with Eimeria parasite infection and will likely affect the host-microbial non-pathogenic and pathogenic molecular interactions.
 
Date 2022-09-05
2022-09-24T11:10:37Z
2022-09-24T11:10:37Z
 
Type Journal Article
 
Identifier Jebessa, E., Guo, L., Chen, X., Bello, S.F., Cai, B., Girma, M., Hanotte, O. and Nie, Q. 2022. Influence of Eimeria maxima coccidia infection on gut microbiome diversity and composition of the jejunum and cecum of indigenous chicken. Frontiers in Immunology 13:994224.
1664-3224
https://hdl.handle.net/10568/121940
https://doi.org/10.3389/fimmu.2022.994224
https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA872932
 
Language en
 
Rights CC-BY-4.0
Open Access
 
Format 12 p.
 
Source Frontiers in Immunology