Marine Macroalga-associated Bacillus amyloliquefaciens as Prospective Probiotic
CMFRI Repository
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Relation |
http://eprints.cmfri.org.in/16644/
https://www.tandfonline.com/doi/full/10.1080/10498850.2021.1974140 https://doi.org/10.1080/10498850.2021.1974140 |
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Title |
Marine Macroalga-associated Bacillus amyloliquefaciens as Prospective Probiotic
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Creator |
Vinaya, K K
Chakraborty, Kajal |
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Subject |
Bacteria
Biochemistry Algae |
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Description |
Heterotrophic Bacillus amyloliquefaciens (MTCC 12716) isolated from the red alga Hypnea valentiae exhibited promising antibacterial activity (minimum inhibitory concentration of ≤1.0 µg/mL) against clinically relevant pathogens. The bacterium displayed bile salt and acid tolerance up to 4 h in a simulated gastric fluid, along with a prospective antioxidant effect. This non-hemolytic bacterium was found to be sensitive to a panel of antibiotics and did not amplify the enterotoxin-specific genes. In order to analyze the possibilities of scaling up, we have optimized the growth of B. amyloliquefaciens by response surface methodology to realize maximum production of anti-infective agents in the fermentation medium and observed an increment of about 85% antibacterial activity against gastrointestinal pathogens. As probiotic treatment is useful due to its ability to recreate the natural intestinal microflora, this heterotrophic Bacillus could be contemplated to offer a prospective probiotic. Further studies are needed to assess its utility for commercial application.
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Publisher |
Taylor and Francis
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Date |
2021
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Type |
Article
PeerReviewed |
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Format |
text
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Language |
en
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Identifier |
http://eprints.cmfri.org.in/16644/1/Journal%20of%20Aquatic%20Food%20Product%20Technology_2021_Kajal%20Chakraborty.pdf
Vinaya, K K and Chakraborty, Kajal (2021) Marine Macroalga-associated Bacillus amyloliquefaciens as Prospective Probiotic. Journal of Aquatic Food Product Technology, 30 (9). pp. 1078-1089. ISSN 1547-0636 |
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