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Voltammetric investigations of functional dyspepsia drug acotiamide at pencil graphite electrode: An eco-friendly and cost effective stripping detection method

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Title Voltammetric investigations of functional dyspepsia drug acotiamide at pencil graphite electrode: An eco-friendly and cost effective stripping detection method
 
Creator Agarwal, Rinky
Yadav, Rajesh
Sharma, Raj Kumar
Sharma, D K
Jhankal, K K
 
Subject Acotiamide
BR buffer
Functional dyspepsia
Pencil graphite electrode
Stripping voltammetry
 
Description 124-130
First time, the electro-oxidative behaviour and determination of acotiamide at a pencil graphite electrode have been
investigated under different experimental conditions using cyclic voltammetry (CV), differential pulse anodic stripping
voltammetry (DPASV), and square wave anodic stripping voltammetric (SWASV) techniques. The voltammetric responses
of acotiamide have been analyzed at different scan rates, pH and concentrations. Oxidation of acotiamide at the surface of
pencil graphite electrode gave two well defined irreversible peaks in the voltammograms in BR buffer of pH 7.0.
The oxidation process is completely diffusion controlled. A linear response of peak current has been obtained between
15.5 to 124 μM in non-aqueous media for all the voltammetric techniques. The proposed DPASV and SWASV techniques
show limit of detection at 18.58 and 13.36 μM, respectively.
 
Date 2023-01-27T06:31:45Z
2023-01-27T06:31:45Z
2023-01
 
Type Article
 
Identifier 0975-0991 (Online); 0971-457X (Print)
http://nopr.niscpr.res.in/handle/123456789/61290
https://doi.org/10.56042/ijct.v30i1.58991
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJCT Vol.30(1) [January 2023]