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A look at trails through the pangenome visualization jungle

CGSpace

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Title A look at trails through the pangenome visualization jungle
 
Creator Durant, Éloi
Sabot, François
Conte, Matthieu
Rouard, Mathieu
 
Subject monitoring systems
digital technology
alternative methods
application equipment
genomic features
tecnología digital
métodos alternativos
equipo de aplicación
 
Description High-throughput sequencing technologies enabled the production of multiple reference genome sequences for a single species. Comparisons of such sequences showed that there are structural variations between individuals from the same species such as Copy Number Variations (CNV) and Presence Absence Variations (PAV) that can have a significant impact on phenotypic variation in plants and could be suitable for breeding improved crop varieties. Thus, a single reference genome is insufficient to capture all variations.
Pangenomics is an integrative approach which aims to the assessment of such genomic variations and more within a group of closely related individuals. Its definition can focus on the whole repertoire of genes within a group or can include blocks of genomic sequences shared between species. We introduce here a new visualization tool, based on a linear representation: the PANgenome Analyzer with CHromosomal Exploration (PANACHE). It is a web-based application which enables its users to explore a pangenomic reference divided in multiple panchromosomes.
 
Date 2021-07-01
2021-07-27T08:28:26Z
2021-07-27T08:28:26Z
 
Type Poster
 
Identifier Durant, É.; Sabot, F.; Conte, M.; Rouard, M. (2021) A look at trails through the pangenome visualization jungle. Presented at BioVis@ISMB, July 26-27, 2021. (http://biovis.net/2021/program_ismb). 1p.
https://hdl.handle.net/10568/114400
 
Language en
 
Rights CC-BY-4.0
Open Access
 
Format 1 p.
application/pdf