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Ameliorative effect of sixteen weeks endurance training on biochemical and oxidative damage in high fat diet induced obese rats

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Title Ameliorative effect of sixteen weeks endurance training on biochemical and oxidative damage in high fat diet induced obese rats
 
Creator Emami, Seyed Reza
Jafari, Mahvash
Haghshenas, Rouhollah
Ravasi, Aliasghar
 
Subject Antioxidants
Lipid peroxidation
Lipid profiles
Obesity
Physical exercise
 
Description 107-115
Obesity is mainly caused by consumption of high fat diet (HFD) and a lack of physical activity. Physical activity is an
efficient strategy to delay development of obesity. In this studyv we tried to evaluate attenuating properties of 16 weeks
endurance training on plasma oxidative stress and some biochemical parameters in HFD induced obese rats. Twenty-four
male Wistar rats were randomly divided into four groups: standard diet group (SD), standard diet with endurance training
group (ESD), HFD group and HFD with endurance training group (EHFD). After sixteen weeks, plasma was prepared and
evaluated for measurement of different parameters. The results showed that HFD significantly decreased the activities of
superoxide dismutase (33.58%), catalase (26.51%) and glutathione S-transferase (22.77%), while endurance training
increased these enzymes activities. However, exercise ameliorated the increased malondialdehyde level and depletion of
glutathione. In addition, it significantly reduced the increased levels of liver enzymes activities and lipid profiles. These
findings suggest that endurance training has found to have beneficial effects against HFD-induced oxidative damage through
increasing reduced antioxidants levels and inhibition of lipid peroxidation due to its antioxidant property. Thus, it can be
considered an interesting strategy for the management of obesity related diseases.
 
Date 2023-01-31T10:20:06Z
2023-01-31T10:20:06Z
2023-01
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/61308
https://doi.org/10.56042/ijeb.v61i02.64101
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.61(02) [Feb 2023]