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Ameliorative effect of sixteen weeks endurance training on biochemical and oxidative damage in high fat diet induced obese rats

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Title Statement Ameliorative effect of sixteen weeks endurance training on biochemical and oxidative damage in high fat diet induced obese rats
 
Added Entry - Uncontrolled Name Emami, Seyed Reza; Department of Biochemistry, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
Jafari, Mahvash
Haghshenas, Rouhollah
Ravasi, Aliasghar
Baqiyatallah University of Medical Sciences
 
Uncontrolled Index Term Antioxidants; Lipid peroxidation; Lipid profiles; Obesity; Physical exercise
 
Summary, etc. Obesity is mainly caused by consumption of high fat diet (HFD) and a lack of physical activity. Physical activity is an efficient strategy to delay development of obesity. In this studyv we tried to evaluate attenuating properties of 16 weeks endurance training on plasma oxidative stress and some biochemical parameters in HFD induced obese rats. Twenty-four male Wistar rats were randomly divided into four groups: standard diet group (SD), standard diet with endurance training group (ESD), HFD group and HFD with endurance training group (EHFD). After sixteen weeks, plasma was prepared and evaluated for measurement of different parameters. The results showed that HFD significantly decreased the activities of superoxide dismutase (33.58%), catalase (26.51%) and glutathione S-transferase (22.77%), while endurance training increased these enzymes activities. However, exercise ameliorated the increased malondialdehyde level and depletion of glutathione. In addition, it significantly reduced the increased levels of liver enzymes activities and lipid profiles. These findings suggest that endurance training has found to have beneficial effects against HFD-induced oxidative damage through increasing reduced antioxidants levels and inhibition of lipid peroxidation due to its antioxidant property. Thus, it can be considered an interesting strategy for the management of obesity related diseases.
 
Publication, Distribution, Etc. Indian Journal of Experimental Biology (IJEB)
2023-01-31 15:04:51
 
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http://op.niscair.res.in/index.php/IJEB/article/view/64101
 
Data Source Entry Indian Journal of Experimental Biology (IJEB); ##issue.vol## 61, ##issue.no## 02 (2023): IJEB [FEBRUARY 2023]
 
Language Note en