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TLR5-Mediated Reactivation of Quiescent Ranavirus FV3 in Xenopus Peritoneal Macrophages.

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Title TLR5-Mediated Reactivation of Quiescent Ranavirus FV3 in Xenopus Peritoneal Macrophages.
Not Available
 
Creator M. Samanta
J. Yim
F. De Jesús Andino
M. Paiola
J. Robert
 
Subject ranaviruses
TLR5 stimulation
amphibian
peritoneal macrophages
Nod-like receptors
 
Description Not Available
This study in the amphibian Xenopus laevis provides new evidence of the critical role of macrophages in the persistence of ranaviruses in a quiescent state as well as in the reactivation of these pathogens into a virulent infection. Among the multiple microbial sensors expressed by macrophages, our data underscore the preponderant involvement of TLR5 stimulation in triggering the reactivation of quiescent FV3 in resident peritoneal macrophages, unveiling a mechanistic connection between the reactivation of persisting ranavirus infection and bacterial coinfection
Not Available
 
Date 2023-02-04T06:23:17Z
2023-02-04T06:23:17Z
2021-04
 
Type Journal
 
Identifier Samanta, M., Yim, J., De Jesús Andino, F., Paiola, M., & Robert, J. (2021). TLR5-Mediated Reactivation of Quiescent Ranavirus FV3 in Xenopus Peritoneal Macrophages. Journal of Virology, 95(12), e00215-21.
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/75998
 
Language English
 
Relation Not Available;
 
Publisher Not Available