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Synthesis and evaluation of biological activity of some novel carbazole derivatives

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Title Synthesis and evaluation of biological activity of some novel carbazole derivatives
 
Creator Kumar, Umesh
Kumar Gupta, Sujeet
Yogi, Bhumika
Kumar Gautam, Surendra
 
Subject Carbazole
Heterocyclic chemistry
Anti-inflammatory activity
Carrageenan induced Inflammation
Rat paw Edema model
Diclofenac sodium
 
Description 60-64
Natural and synthetic carbazoles contains potent activity against inflammation. Some novel carbazole derivatives have
been synthesized and also checked for activity against inflammation by using Carrageenan Induced Inflammation in Rat
Paw Edema Model. Structures of synthesized carbazole derivatives have been confirmed on the basis of FT-IR, 1H NMR
and elemental analysis. During the evaluation of biological activity, newly synthesized compounds (4a) and (4f) are found
more potent against inflammation.
 
Date 2023-02-09T10:27:07Z
2023-02-09T10:27:07Z
2023-01
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61374
https://doi.org/10.56042/ijc.v62i1.70394
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.62(01) [Jan 2023]