Synthesis, characterization, antimicrobial and antitubercular activity of some new pyrimidine derivatives
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Title |
Synthesis, characterization, antimicrobial and antitubercular activity of some new pyrimidine derivatives
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Creator |
Desai, Siddharth
Sastry, Girija Singh Chatrapati, Kishore |
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Subject |
Chalcones
Pyrimidines Antimicribial activity Antitubercular activity Microplate Alamar Blue Assay |
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Description |
11-15
Pyrimidine heterocycles are proven to be biologically active heterocycles, found in many biological systems, displaying a broad spectrum of biological activities including anticancer, anxiolytic, antioxidant, antiviral, antifungal, anticonvulsant, antidepressant and antibacterial activities. New substituted 2-oxopyrimidines have been synthesized from the chalcones linked via indane-1,3-dione moity by the methods discussed in experimental section. We have synthesized some new 2-[6- (substituted phenyl)-2-oxo-1,2,5,6-tetrahydropyrimidin-4-yl]-indane-1,3-dione by reacting chalcones (step-1 compounds have been reported by us) with urea. |
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Date |
2023-02-09T11:18:59Z
2023-02-09T11:18:59Z 2023-01 |
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Type |
Article
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Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61382 https://doi.org/10.56042/ijc.v62i1.70345 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJC Vol.62(01) [Jan 2023]
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