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Synthesis, characterization, antimicrobial and antitubercular activity of some new pyrimidine derivatives

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Title Synthesis, characterization, antimicrobial and antitubercular activity of some new pyrimidine derivatives
 
Creator Desai, Siddharth
Sastry, Girija
Singh Chatrapati, Kishore
 
Subject Chalcones
Pyrimidines
Antimicribial activity
Antitubercular activity
Microplate Alamar Blue Assay
 
Description 11-15
Pyrimidine heterocycles are proven to be biologically active heterocycles, found in many biological systems, displaying
a broad spectrum of biological activities including anticancer, anxiolytic, antioxidant, antiviral, antifungal, anticonvulsant,
antidepressant and antibacterial activities. New substituted 2-oxopyrimidines have been synthesized from the chalcones
linked via indane-1,3-dione moity by the methods discussed in experimental section. We have synthesized some new 2-[6-
(substituted phenyl)-2-oxo-1,2,5,6-tetrahydropyrimidin-4-yl]-indane-1,3-dione by reacting chalcones (step-1 compounds
have been reported by us) with urea.
 
Date 2023-02-09T11:18:59Z
2023-02-09T11:18:59Z
2023-01
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61382
https://doi.org/10.56042/ijc.v62i1.70345
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.62(01) [Jan 2023]