ICAR Research Data Repository for Knowledge Management
Anti-inflammatory effect of epidermal growth factor conjugated silk fibroin immobilized polyurethane ameliorates diabetic burn wound healing
KRISHI: Publication and Data Inventory Repository
View Archive Info| Field | Value | |
| Title |
Anti-inflammatory effect of epidermal growth factor conjugated silk fibroin immobilized polyurethane ameliorates diabetic burn wound healing
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| Creator |
Parveen Maurye
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| Subject |
Anti-inflammatory effect,epidermal growth factor,silk fibroin,wound healing
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| Description |
Not Available
Few studies are reported on immunomodulatory potential of non-mulberry (Antheraea mylitta) silk fibroin (SF) combined with polyurethane (PU) in diabetic wound healing. In this study, PU/SF (Antheraea mylitta) scaffolds were fabricated by blending and immobilization techniques. Effective SF dosage was determined and incorporated according to minimum inhibitory concentrations against wound associated bacterial strains while fabricating scaffold. Dermal fibroblast NIH3T3 cells were seeded on epidermal growth factor (EGF) treated and untreated PU/SF scaffolds, fabricated by blending and immobilization techniques. Fibroblast seeded PU/SF scaffolds were investigated for anti-inflammatory response in wound recovering potential comparing with Acticoat? in third degree burn of streptozotocin induced diabetic rats. At 16th, 24th days, promising healing was achieved with faster granulation, enhanced ? |
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| Date |
2021-04-29T12:14:16Z
2021-04-29T12:14:16Z 2020-5-1 |
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| Type |
Research Paper
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| Identifier |
Not Available
0141-8130 http://krishi.icar.gov.in/jspui/handle/123456789/46865 |
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| Language |
English
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| Relation |
14
14 |
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| Publisher |
Not Available
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