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Quantitative imaging of arsenic and its species in goat following long term oral exposure.

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Title Quantitative imaging of arsenic and its species in goat following long term oral exposure.
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Creator Patra, P.H.,
Bandyopadhyay, S.,
Kumar, R.,
Datta, B.K.,
Maji, C.,
Biswas, S.,
Dash, J.R.,
Sar, T.K.,
Sarkar,S.,
Manna, S.K.,
Chakraborty, A.K.
Mandal, T.K.
 
Subject arsenic
oral exposure
species in goat
 
Description Not Available
Severity of arsenic toxicity was reported to vary depending on its species. The present study reflects the status of different species of arsenic in goat following long-term exposure of arsenic leading to hepatic damage. The experiment was conducted with six black Bengal goats, which were administered with sodium arsenite orally at a dose rate of 2 mgkg(-1) daily for 84 days. Faeces, urine, hair and blood samples were collected from those animals at 14 days interval. Excretion of total arsenic was reduced from 56 days onwards through both faeces and urine indicating higher accumulation of arsenic in body. The speciation study revealed that urinary arsenic was mainly of organic type, whereas hair accumulated almost equal proportion of arsenite, arsenate and organo arsenicals. Goats excreted high proportion of organo arsenicals through faeces possibly due to hepatobiliary secretion of organo arsenic into the gut. Significantly elevated serum alanine aminotransferase and aspartate aminotransferase activities (p
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Date 2019-09-25T16:21:46Z
2019-09-25T16:21:46Z
2012-06-01
 
Type Research Paper
 
Identifier Patra, P.H., Bandyopadhyay, S., Kumar, R., Datta, B.K., Maji, C., Biswas, S., Dash, J.R., Sar, T.K., Sarkar,S., Manna, S.K., Chakraborty, A.K. and Mandal, T.K. 2012. Quantitative imaging of arsenic and its species in goat following long term oral exposure. Food and Chemical Toxicology, 50: 1946-1950.
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http://krishi.icar.gov.in/jspui/handle/123456789/23099
 
Language English
 
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Publisher Not Available