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Use of fish model in modern biological experimentation: Synthesis and review

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Title Use of fish model in modern biological experimentation: Synthesis and review
Not Available
 
Creator Asit Kumar Bera
Uttam Kumar Sarkar
Debendra Nath Dey
Sadrupa Bhowmick
Basanta Kumar Das
 
Subject Danio rerio, Killifish, Metadata, Biomedical research
 
Description Not Available
Globally animal models play very important role in the progress of life science in
a wide range of biological experimentations. Suitability of different animal model relies on
its similarity in genetic makeup, resemble physiological response on diseases of multiple
etiology and different drugs, easy maintenance of model animal. Among the fishes, zebrafish
and some other species like killifish and cave fish has been found to have great potential and
being experimented as an alternative model animal for experimentation of some specific
human diseases. Metadata analysis with relevant keywords revealed >8000 research
publications on fish model in last 12 years. In India, zebrafish, Danio rerio (Hamilton, 1822),
is widely distributed. However, very less attention has so far been paid to understand the
importance of the species in biological experimentation except few scattered reports. Besides
zebrafish, use of African killifish and cave fish has also been outlined. The present paper
synthesized the current knowledge of research and discussed the status and potentials of fish
as a model in modern biological experimentation in various medical disorders and
recommends their utilization for drug discovery and critical human disease modelling.
Not Available
 
Date 2021-08-13T04:48:26Z
2021-08-13T04:48:26Z
2020-10-29
 
Type Review Paper
 
Identifier Bera, A.K.; Sarkar, U.K.; Dey, D.N.; Bhowmick S. & Das, B.K. 2020. Use of fish model in modern biological experimentation: Synthesis and review. Iranian Journal of Ichthyology 7(4): 280-297.
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/56207
 
Language English
 
Relation Not Available;
 
Publisher Not Available