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<p>Synthesis, spectral, antibacterial and docking analyses of (3,4-bis((<em>E</em>)-(arylidene)amino)phenyl)(phenyl)methanones</p>

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Title Statement <p>Synthesis, spectral, antibacterial and docking analyses of (3,4-bis((<em>E</em>)-(arylidene)amino)phenyl)(phenyl)methanones</p>
 
Added Entry - Uncontrolled Name Muthuvel, I ; Department of Chemistry, Annamalai University, Annamalainagar 608 002, India Department of Chemistry, M.R. Government Arts College, Mannargudi 614 001, India
Manikanadan, S ; Department of Chemistry, Annamalai University, Annamalainagar 608 002, India
Thirunarayanan, G ; Department of Chemistry, Annamalai University, Annamalainagar 608 002, India
Usha, V ; Department of Chemistry, University College of Engineering Panruti, Panruti 607 106, India
Sathiyendiran, V ; Department of Chemistry, Sourashtra College, Madurai 625 004, India
 
Uncontrolled Index Term Schiff bases, IR spectra, NMR spectra, Antibacterial activity, Docking study
 
Summary, etc. <p style="text-align: justify;">Biologically active Schiff bases namely (3,4-bis((<em>E</em>)-(arylidene)amino) phenyl)(phenyl)methanones have been synthesized through ultrasonicated condensation of (3,4-diaminophenyl)(phenyl)methanone and various benzaldehydes in ethanol medium. Synthesised Schiff bases have been examined by different techniques like molecular formula calculation, molecular weight determination, melting point determination, micro analysis and spectroscopic data. The <em>in vitro</em> antibacterial actions of these <em>E</em>-imines have been assessed against bacterial strains by zone inhibition and serial dilution methods. Further, molecular docking analysis of all <em>E</em>-imines have been accomplished to comprehend the order of binding of Schiff bases with protein.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2023-02-23 17:43:13
 
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http://op.niscair.res.in/index.php/IJC/article/view/71254
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 62, ##issue.no## 2 (2023): Indian Journal of Chemistry-(IJC)
 
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