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<p>A novel approach to determine anti-proliferative, anti-migratory and anti-microbial properties of 2-phenylethylammonium carboxylate molecular salts</p>

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Title Statement <p>A novel approach to determine anti-proliferative, anti-migratory and anti-microbial properties of 2-phenylethylammonium carboxylate molecular salts</p>
 
Added Entry - Uncontrolled Name Akbaş, Hüseyin ; Tokat Gaziosmanpaşa University, Science and Arts Faculty, Department of Chemistry, Tokat, Turkey
Tayhan, Seçil Erden; Tokat Gaziosmanpaşa University, Faculty of Engineering and Architecture, Department of Genetic and Bioengineering, Tokat, Turkey
Bilgin, Sema ; Tokat Gaziosmanpaşa University, Tokat Health Services Vocational School, Department of Medical Services and Techniques, Tokat, Turkey
 
Uncontrolled Index Term Antibacterial effect, Antimigratory effect, Antiproliferative effect, Cancer, Salt, Spectroscopy
 
Summary, etc. <p class="Abstract" style="text-align: justify;"><span lang="EN-GB">2-Phenylethylammonium (PEA) salt derivatives have been prepared between 2-phenylethylamine with various aromatic carboxylic acids (nicotinic, benzoic, salicylic, and γ-resorcylic) and confirmed by spectroscopic analyses. Additionally, the possible biological activities of these salts have been examined and the antiproliferative and antimigrative effects of salts on breast and colon cancer cell lines have been determined. Furthermore, to obtain preliminary data for the effects of the indicated compounds on cancer angiogenesis, <em>in vitro</em> migration analysis has been performed by human vascular endothelial cells. The antibacterial effects of the compounds have also been investigated. Therefore, an important contribution has been made to studies conducted to better recognize the pharmacological effects of salts.</span></p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2023-03-17 15:15:07
 
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http://op.niscair.res.in/index.php/IJC/article/view/72069
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 62, ##issue.no## 3 (2023): Indian Journal of Chemistry-(IJC)
 
Language Note en