Anti-inflammatory, analgesic and antitubercular activity of 4,6-diphenyl-4,5,6, 7-tetrahydro-3-selena-1,2,5-triazo-indene derivativesS
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Title |
Anti-inflammatory, analgesic and antitubercular activity of 4,6-diphenyl-4,5,6, 7-tetrahydro-3-selena-1,2,5-triazo-indene derivativesS
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Creator |
Balasubramanian, S
Jayalakshmi, N |
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Subject |
Selenatriazoindene
Anti-inflammatory Aanalgesic Antitubercular activities |
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Description |
202-206
Several 4,6-diphenyl-4,5,6,7-tetrahydro-3-selena-1,2,5-triazo-indene derivatives have been synthesized by the Mannich reaction (condensation) of ethyl methyl ketone, substituted aldehyde and ammonium acetate and selenium dioxide. The chemical structures have been confirmed by means of IR, 1H NMR and mass spectral data. The synthesized compounds have been evaluated for anti-inflammatory, analgesic and antitubercular activity. The compounds have emerged as the most promising active compounds to that of standards. In addition, the inhibition effect increases with the increase in concentration of these compounds. |
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Date |
2023-03-17T07:33:12Z
2023-03-17T07:33:12Z 2023-03 |
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Type |
Article
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Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61544 https://doi.org/10.56042/ijc.v62i3.72068 |
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Language |
en
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Publisher |
NIScPR-CSIR,India
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Source |
IJC Vol.62(03) [Mar 2023]
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