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Differential miRNA expression profiling of highly pathogenic avian influenza virus H5N1 infected chicken lungs reveals critical microRNAs, biological pathways and genes involved in the molecular pathogenesis

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Title Differential miRNA expression profiling of highly pathogenic avian influenza virus H5N1 infected chicken lungs reveals critical microRNAs, biological pathways and genes involved in the molecular pathogenesis
Not Available
 
Creator Mishra A,
Asaf M,
Kumar A,
Kulkarni DD,
Sood R,
Bhatia S,
Bhushan B,
Raut AA.
 
Subject H5N1 pathogenesis
 
Description Not Available
Highthrouput sequencing of small RNA of H5N1 infected and mock infected chicken lungs.
297 miRNAs identified in mock-infected and 201 miRNAs identified in AIV infected chicken lungs.
36 miRNAs were upregulated and 90 were downregulated during H5N1 infection.
Functional analysis and gene ontology of predicted target genes of expressed miRNAs.
MAPK pathway, NF-κB, IGF and gga-let-7b might play important role during H5N1 pathogenesis.
Not Available
 
Date 2023-04-04T06:59:32Z
2023-04-04T06:59:32Z
2022-06-01
 
Type Journal
 
Identifier Mishra, A., Asaf, M., Kumar, A., Kulkarni, D. D., Sood, R., Bhatia, S., Bhushan, B., & Raut, A. A. (2022). Differential miRNA expression profiling of highly pathogenic avian influenza virus H5N1 infected chicken lungs reveals critical microRNAs, biological pathways and genes involved in the molecular pathogenesis. Virologica Sinica, 37(3)
1674-0769
http://krishi.icar.gov.in/jspui/handle/123456789/76664
 
Language English
 
Relation Not Available;
 
Publisher Beijing : Science Press